Melua is signed to the small Dramatico record label, under the management of composer Mike Batt, and made her musical debut in 2003. In 2006, she was the United Kingdom's best-selling female artist and Europe's highest selling European female artist.
In November 2003, at the age of nineteen, Melua released her first album, Call Off the Search, which reached the top of the United Kingdom album charts and sold 1.8 million copies in its first five months of release. Her second album, Piece by Piece, was released in September 2005 and to date has gone platinum four times. Melua released her third studio album Pictures in October 2007.